Chinese: Si Ni San
English: Frigid Extremities Powder
Source: Shanghanlun (Treatise on Cold Damage Diseases)
Pulse: bowstring
Tongue: red body, yellow coating
Abdomen:kyokyokuman, fukuchokukinrenkyu
Indications: This herbal formula has been used for patients with following health conditions and symptoms:
- Cold extremities
- Irritability
- Poor appetite
- Abdominal pain
- Nervousness
There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.
Abdominal pattern (fukusho) of Shigyakusan (from Fukusho Kiran, 1800)

Basic and Clinical Research on Shigyakusan – Updated on Mar. 30, 2011
Watanabe H. A study of peptic ulcer maintenance therapy combined with Kampo medicines. Kampo Igaku (Kampo Medicine) 1995; 19: 18-21.
Sakurada T, Ikeda K, Takasaka T, et al. Clinical effectiveness of Kampo medicine for chronic rhinitis and sinusitis. Jibiinkoka Rinsho (Practica otologica) 1992; 85: 1341-6.
Inoue M. Kampo therapy for mastitis – shigyakusan. Kampo Igaku (Kampo Medicine) 1990; 14: 132-6.
