{"id":1171,"date":"2011-02-28T11:47:06","date_gmt":"2011-02-28T15:47:06","guid":{"rendered":"http:\/\/kampo.ca\/herbs-formulas\/"},"modified":"2015-07-25T17:32:09","modified_gmt":"2015-07-25T21:32:09","slug":"orengedokuto","status":"publish","type":"page","link":"https:\/\/kampo.ca\/herbs-formulas\/formulas\/orengedokuto\/","title":{"rendered":"Orengedokuto"},"content":{"rendered":"<!--CusAds0--><p><img loading=\"lazy\" decoding=\"async\" title=\"Huang Lian Jie Du Tang - Coptis Decoction to Reliebve Toxicity\" onmouseup=\"hl2l(event);\" alt=\"Orengedokuto \" src=\"http:\/\/kampo.ca\/herbs-formulas\/wp-content\/uploads\/2011\/02\/Orengedokuto-23.jpg\" width=\"448\" height=\"314\" \/><\/p>\n<p><strong>Chinese:<\/strong> Huang Lian Jie Du Tang<\/p>\n<p><strong>English:<\/strong> Coptis Decoction to Reliebve Toxicity<\/p>\n<p><strong>Source:<\/strong> <a title=\"Medical Secrets of an Official Library\" href=\"http:\/\/kampo.ca\/herbs-formulas\/kampo-and-chinese-medicine-classics\/waitaimiyao\/\"><em>Waitaibiyao<\/em> (Medical Secrets of an Official Library)<\/a><\/p>\n<p><strong>Pulse:<\/strong> Rapid, forceful<\/p>\n<p><strong>Tongue:<\/strong> Red body, yellow fur<\/p>\n<p><strong>Abdomen: <\/strong><a href=\"http:\/\/kampo.ca\/herbs-formulas\/diagnosis\/abdominal-diagnosis\/shinkahiko\/\">Shinkahiko<\/a><\/p>\n<p><strong>Indications:<\/strong> This herbal formula has been used for patients with following health conditions and symptoms:<\/p>\n<ul>\n<li>High fever<\/li>\n<li>Dry mouth and throat<\/li>\n<li>Irritability<\/li>\n<li>Dark urine<\/li>\n<li>Carbuncles<\/li>\n<li>furuncles<\/li>\n<li>Insomnia<\/li>\n<li>Indigestion<\/li>\n<li>Heartburns<\/li>\n<li>Gastritis<\/li>\n<\/ul>\n<p>There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.<\/p>\n<p><b>Herbs in This Formula<\/b><\/p>\n<ul>\n<li><a href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/obaku\/\">Obaku (Phellodendri Cortex)<\/a>, 3g<\/li>\n<li><a href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/ogon\/\">Ogon<\/a>\u00a0(<a href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/ogon\/\">Scutellariae Radix)<\/a>\u00a03g<\/li>\n<li><a href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/oren\/\">Oren<\/a>\u00a0(<a href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/oren\/\">Coptidis Rhizoma<\/a>) 2g<\/li>\n<li><a title=\"gardenia fruit\" href=\"http:\/\/kampo.ca\/herbs-formulas\/herbs\/sanshishi\/\">Sanshishi (Gardeniae Fructus)<\/a>\u00a02g<\/li>\n<\/ul>\n<p><b>Note:<\/b>\u00a0Suggested dosages of each herb in Kampo formulas are often smaller than those of Traditional Chinese Medicine (TCM). Individual dosages of herbs may be adjusted depending on each patient\u2019s condition, constitutional patterns, quality of the herbs, and other factors involved.<\/p>\n<p><strong>Basic and Clinical Research on Orengedokuto (<\/strong><strong>Huang Lian Jie Du Tang<\/strong><strong>)<\/strong> \u2013 Updated on Mar. 30, 2011<\/p>\n<p>Zeng, H.<em>, et al.<\/em> Huang-Lian-Jie-Du-Tang exerts anti-inflammatory effects in rats through inhibition of nitric oxide production and eicosanoid biosynthesis via the lipoxygenase pathway. <em>The Journal of pharmacy and pharmacology<\/em> <strong>61<\/strong>, 1699-1707 (2009).<\/p>\n<p>Park, S., Hong, S.M., Ahn, I.S., Kim, Y.J. &amp; Lee, J.B. Huang-Lian-Jie-Du-Tang supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce improved glucose tolerance by potentiating insulinotropic actions in islets in 90% pancreatectomized diabetic rats. <em>Bioscience, biotechnology, and biochemistry<\/em> <strong>73<\/strong>, 2384-2392 (2009).<\/p>\n<p>Li, X.<em>, et al.<\/em> Huang-Lian-Jie-Du-Tang inhibits myocardial remodeling in a rat model of metabolic syndrome. <em>Journal of ethnopharmacology<\/em> <strong>119<\/strong>, 259-265 (2008).<\/p>\n<p>Hsu, Y.L.<em>, et al.<\/em> Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo. <em>Journal of gastroenterology and hepatology<\/em> <strong>23<\/strong>, e290-299 (2008).<\/p>\n<p>Zhang, D.M.<em>, et al.<\/em> In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier. <em>The Journal of pharmacy and pharmacology<\/em> <strong>59<\/strong>, 1733-1738 (2007).<\/p>\n<p>Lu, T.<em>, et al.<\/em> Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. <em>Journal of ethnopharmacology<\/em> <strong>110<\/strong>, 412-418 (2007).<\/p>\n<p>Arakawa K, Saruta T, Abe K, et al. Improvement of accessory symptoms of hypertension by TSUMURA Orengedokuto Extract, a four herbal drugs containing Kampo-Medicine Granules for ethical use: a double-blind, placebo-controlled study. <em>Phytomedicine <\/em> <strong>13<\/strong>: 1-10 (2006).<\/p>\n<p>Ma, Z.<em>, et al.<\/em> Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. <em>Blood<\/em> <strong>105<\/strong>, 3312-3318 (2005).<\/p><!--CusAds0-->\n<p>Arakawa K, Saruta T, Abe K, et al. Double-blind placebo-controlled trial of TSUMURA Orengedokuto (TJ-15) for the treatment of accessory symptoms of hypertension. <em>Rinsho to Kenkyu <\/em>(<em>Japanese Journal of Clinical and Experimental Study<\/em>) <strong>80<\/strong>: 354-72 (2003)<\/p>\n<p>Ikeda N, Hayasaka S, Nagaki Y, et al. Effects of traditional Sino-Japanese herbal medicines on aqueous flare elevation after small-incision cataract surgery. <em>Journal of Ocular Pharmacology and Therapeutics <\/em><strong>17<\/strong>: 59-65 (2001).<\/p>\n<p>Akiyama Y, Ohno S, Asaoka T, et al. The combination therapy with sarpogrelate hydrochloride and Kampo medicine (oren-gedoku-to or toki-shakuyaku-san) for Raynaud&#8217;s phenomenon. <em>Japanese Journal of Oriental Medicine<\/em> <strong>51<\/strong>: 1101-8 (2001).<\/p>\n<p>Xu, J.<em>, et al.<\/em> Protective effect of Oren-gedoku-to (Huang-Lian-Jie-Du-Tang) against impairment of learning and memory induced by transient cerebral ischemia in mice. <em>Journal of ethnopharmacology<\/em> <strong>73<\/strong>, 405-413 (2000).<\/p>\n<p>Yamada K. 3. Kampo treatment in psychiatry. In: Role of Kampo medicines on the stress-related disorders in a modern society. <em>Nihon Toyo Igaku Zasshi <\/em>(<em>Kampo Medicine<\/em>) <strong>49<\/strong>: 774-80 (1999).<\/p>\n<p>Yamada K, Kanba S, Ohnishi K, et al. Clinical effectiveness of Oren-Gedoku-To for sleep disorder associated with acute schizophrenia and other psychotic disorders. <em>Nihon Toyo Igaku Zasshi <\/em>(<em>Japanese Journal of Oriental Medicine<\/em>) <strong>47<\/strong>: 827-31 (1997).<\/p>\n<p>Narumi J, Kohsaka S, Miyazawa S, et al. Evaluation of the Kampo monotreatment for hypertensive patients using ambulatory blood pressure monitoring. <em>Kampo Shinryo <\/em><strong>15<\/strong>: 34-5 (1996).<\/p>\n<p>Narumi J, Kohsaka S, Miyazawa S, et al. Evaluation of the Kampo monotreatment for hypertensive patients using ambulatory blood pressure monitor. <em>Wakan Iyakugaku Zasshi <\/em>(<em>Journal of Traditional Medicines<\/em>) <strong>11<\/strong>: 282-3 (1994).<\/p>\n<p>Ohkuma M. Treatment of pruritus by Chinese drugs with external application and oral antihistamine. <em>Wakan Iyakugaku Zasshi <\/em>(<em>Journal of Traditional Medicines<\/em>) <strong>11<\/strong>: 302-3 (1994).<\/p>\n<p>Ohkuma M. Treatment of pruritus by Chinese drugs. <em>Wakan Iyaku Gakkaishi <\/em>(<em>Journal of Medical and Pharmaceutical Society for WAKAN-YAKU<\/em>) <strong>10<\/strong>: 126-30 (1993).<\/p>\n<p>Ohkuma M. Treatment of acne by Chinese drugs and external application. <em>Wakan Iyaku Gakkaishi <\/em>(<em>Journal of Medical and Pharmaceutical Society for WAKAN-YAKU<\/em>) <strong>10<\/strong>: 131-4 (1993).<\/p>\n<p>Ohkuma M. Treatment of acne by Chinese drugs and external application &#8211; comparison with oral antibiotics -. <em>Nihon Toyo Igaku Zasshi <\/em>(<em>Japanese Journal of Oriental Medicine<\/em>) <strong>44<\/strong>: 173-7 (1993).<\/p>\n<p>Araki G. Effects of TSUMURA Orengedokuto for sequelae of cerebrovascular accident*. <em>Geriatric Medicine<\/em>; <strong>29<\/strong>: 1587-99 (1991)<\/p>\n<p>Otomo E, Togi H, Kogure K, et al. Clinical usefulness of TSUMURA Orengedokuto for the treatment of cerebrovascular disease: a well-controlled study comparing TSUMURA Orengedokuto versus Ca hopantenate, using sealed envelopes for allocation. <em>Geriatric Medicine <\/em><strong>29<\/strong>: 121-51 (1991).<\/p>\n<p>Ohkawara A, Furuya K, Kurisu Y, et al. Experience with orengedokuto (TJ-15) and goshajinkigan (TJ-107) for the treatment of senile pruritus. <em>Nishinihon Hifuka <\/em>(<em>The Nishinihon Journal of Dermatology<\/em>) <strong>53<\/strong>: 1234-41 (1991).<\/p>\n<p>Ito E, Takahashi A, Kuzuya F. Clinical effectiveness of TSUMURA Orengedokuto in the treatment of cerebral infarction. <em>Geriatric Medicine<\/em> <strong>29<\/strong>: 303-13 (1991).<\/p>\n<p>Kaneko H, Nakanishi K, Murakami A, et al. Clinical evaluation of the effect of Ohrengedoku-Toh and Ohrengedoku-Toh &#8211; Red Ginseng mixture on chronic cardiovascular disorders in middle and aged patients. <em>The Ginseng Review <\/em><strong>12:<\/strong> 89-93 (1991).<\/p>\n<div class=\"1105701a103637095f64f2405c549ac8\" data-index=\"1\" style=\"float: none; margin:5px 0 5px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block; text-align:center;\"\r\n     data-ad-layout=\"in-article\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-client=\"ca-pub-3630309833918220\"\r\n     data-ad-slot=\"2018820141\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Shichido T, Arichi S. Preventive effects of Kampo medicine (orengedokuto) on hangover &#8211; a double-blind randomized pilot study. <em>Igaku no Ayumi <\/em>(<em>Journal of Clinical and Experimental Medicine<\/em>) <strong>145<\/strong>: 789-95 (1998).<\/p>\n<!--CusAds0-->\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Chinese: Huang Lian Jie Du Tang English: Coptis Decoction to Reliebve Toxicity Source: Waitaibiyao (Medical Secrets of an Official Library) Pulse: Rapid, forceful Tongue: Red body, yellow fur Abdomen: Shinkahiko Indications: This herbal formula has been used for patients with&nbsp;&hellip; <a href=\"https:\/\/kampo.ca\/herbs-formulas\/formulas\/orengedokuto\/\">finish&nbsp;reading&nbsp;Orengedokuto<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":27,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1171","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Orengedokuto<\/title>\n<meta name=\"description\" content=\"Chinese: Huang Lian Jie Du Tang English: Coptis Decoction to Reliebve Toxicity Source: Waitaibiyao (Medical Secrets of an Official Library) Pulse: Rapid,\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kampo.ca\/herbs-formulas\/formulas\/orengedokuto\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta 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