Chinese: Wu Ling San

English: Five Ingredient Powder with Poria

Source: Shanghanlun (Treatise on Cold Damage Diseases)

Pulse: floating or floating and slippery

Tongue: wet white fur or white greasy fur

Abdomen: mild shinkahiko or shinsuion

Indications: This herbal formula has been used for patients with following health conditions and symptoms:

  • Scanty urination
  • Edema
  • Swollen eyelids
  • Difficult urination
  • Thirst
  • Headache
  • Irritability
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Hangover

There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.

Herbs in This Formula

Note: Suggested dosages of each herb in Kampo formulas are often smaller than those of Traditional Chinese Medicine (TCM). Individual dosages of herbs may be adjusted depending on each patient’s condition, constitutional patterns, quality of the herbs, and other factors involved.

Abdominal pattern (fukusho) of Goreisan (from Fukusho Kiran Yoku 1809)

Basic and Clinical Research on Goreisan (Wu Ling San) – Updated on Mar. 30, 2011

Yoshida M. Efficacy of goreisan suppository. Nihon Syoni Toyo Igakkaishi (The Japan Pediatric Society for Oriental Medicine) 19: 13-7 (2003)

Yoshida M. Efficacy of goreisan suppository for vomiting in young children. Toyoigaku (Japanese Journal of Oriental Medicine) 28: 36-8 (2000)

Nakamura H, Nakamura T, Nakagawa S et al. Efficacy of goreisan in treatment of orthostatic hypotension in patients with diabetes mellitus Diabetes Frontier 2000; 11: 561-3 (2000)

Nishi K, Takata K, Asano S, et al. Effects of goreisan suppository on vomiting in children – comparison with domperidone suppository. Nihon Byoin Yakuzaishikai Zasshi (Journal of Japanese Society of Hospital Pharmacists) 34: 1173-6 (1998)

Yoshimura K, Miyake O, Okuyama A, et al. Effect of chorei-to and gorei-san on calcium oxalate crystallization in human urine. Hinyokika Kiyo (Acta Urologica Japonica) 44: 13-6 (1998)

Ishioka T. Comparison of the efficacy of goreisan and saireito for mild edema of the dorsum of the foot in elderly subjects stratified by physical strength. Kampo no Rinsho (Journal of Kampo Medicine) 44: 1091-5 (1997)

Seki M, Fujioka M, Hatano T, et al. Differences between the effects of Sho-saiko-to, Gorei-san, and Toki-shakuyaku-san on the sphincter of Oddi – An intraoperative cholangiomanometric study. Nihon Toyo Igaku Zasshi (Japanese Journal of Oriental Medicine) 43: 395-402 (1993)

Takagi S. Increase of urinary 6-keto-prostaglandin F1level by preoperative administration of Gorei-san or Toki-shakuyaku-san to the patients of gallbladder stones or polyps. Wakan Iyaku Gakkaishi (Journal of Medical and Pharmaceutical Society for WAKAN-YAKU) 9: 32-9 (1992)

Seki M, Fujioka M, Hatano T, et al. Analysis of regulatory effects of Gorei-san on circulatory, metabolic and diuretic function – especially in relation to endothelial activation and increase of urinary 6-keto-prostaglandin F1 level. Nihon Toyo Igaku Zasshi (Japanese Journal of Oriental Medicine) 42: 313-22 (1992)

Otake T, Kato I, Saito S, et al. The prophylactic effect of “Gosyuyu-to” and “Gorei-san” for post-spinal headache. Pain Clinic 12: 648-52 (1991)

Seki M. Efficacy of goreisan for preventing thrombocytopenia and activating vascular endothelial cells after cholecystectomy. Wakan Iyaku Gakkaishi (Journal of Medical and Pharmaceutical Society for WAKAN-YAKU) 7: 510-1 (1990)

Takagi S. Mitigation of hyponatremia after operation for cholelithiasis or gallbladder polyp by preoperative administration of Wu-Ling-San. Journal of Saitama Medical School 17: 145-50 (1990)