Chinese: Chai Po Tang
English: Combined Minor Buplerum Decoction and Pinellia and Magnolia Bark Decoction
Pulse: bowstring, rapid
Tongue: red body, thin, white fur
Indications: This herbal formula has been used for patients with following health conditions and symptoms:
- Plum-pit qi (a feeling of something caught in the throat)
There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.
Herbs in This Formula
- Hange (Pinelliae Rhizoma), 5g
- Bukuryo (Sclerotium Poriae Cocos), 5g
- Shokyo (Zingiberis Rhizoma recens), 4g
- Koboku (Magnoliae officinalis Cortex), 3g
- Shisoyo (Perillae Folium), 2g
- Ninjin (Ginseng Radix) 2g
- Saiko (Bupleuri Radix) 6g
- Ogon (Scutellariae Radix) 3g
- Taiso (Jujubae Fructus) 2g
- Shakanzo (Glycyrrhizae Radix preparata) 2g
Note: Suggested dosages of each herb in Kampo formulas are often smaller than those of Traditional Chinese Medicine (TCM). Individual dosages of herbs may be adjusted depending on each patient’s condition, constitutional patterns, quality of the herbs, and other factors involved.
Basic and Clinical Research on Saibokuto – Updated on Mar. 30, 2011
Nishizawa Y, Nishizawa Y, Yoshioka F, et al. Clinical effect of chai-po-tang (Japanese name: saiboku-to), a Chinese tracitional herbal medicine, in patients with bronchial asthma and autonomic nerve dysfunction: a multicenter, randomized, double-blind, placebo-controlled study. Nihon Toyo Shinshin Igaku Kenkyu (Journal of Japanese Association of Oriental and Psychosomatic Medicine) 2004; 19:37-41.
Nishizawa Y, Nishizawa Y, Yoshioka F, et al. Clinical effect of a Kampo medicine, chai-po-tang (Japanese name: saiboku-to) compared with xiao-quing-long tang (Japanese name: shoseiryu-to) in asthmatics with anxiety and depression due to asthmatic attacks. Nihon Toyo Shinshin Igaku Kenkyu (Journal of Japanese Association of Oriental Psychosomatic Medicine) 2003; 18: 11-7.
Urata Y, Yoshida S, Irie Y, et al. Treatment of asthma patients with herbal medicine TJ-96: a randomized controlled trial. Respiratory Medicine 2002; 96: 469-74.
Nishizawa Y, Nishizawa Y, Yoshioka F, et al. Clinical effect of a Chinese tracitional herbal medicine, chai-po-tang (Japanese name: saiboku-to) compared with clotiazepam in patients with bronchial asthmatics and anxiety disorder in multicenter randomized, comparative trial. Nihon Toyo Shinshin Igaku Kenkyu (Journal of Japanese Association of Oriental Psychosomatic Medicine) 2002; 17: 20-7.
Nishizawa Y, Nishizawa Y, Nagano F, et al. Sparing effect of saibokuto inhalation on inhaled beclomethasone dipropionate to halved of reduction of inhaled beclomethasone dipropinate-dose: well-controlled comparative study of saiboku-to-inhalation and sodium cromoglycate-inhalation. Jibi-inkoka Tenbo (Oto-rhino-laryngology Tokyo) 2002; 45: 8-15.
Nishizawa Y, Nishizawa Y, Goto HG. Chronic pain in intractable and chronic medical conditions. Mansei Totsu (The Journal of the Japanese Society for the Study of Chronic Pain) 2002; 21: 67-77.
Nishizawa Y, Nishizawa Y, Yoshioka F, et al. Suppressive Effect of Japanese Herbal Medicine, Saiboku-to (Cai-Pu-Tang) on Brochospasms in Aspirin-induced Bronchial Asthmatic Patients. A Randomized, Double-blind Test. Jibi-inkoka Tenbo (Oto-Rhino-Laryngology Tokyo) 2001; 44: 5-13.
Nishizawa Y, Nishizawa Y, Yoshioka F, et al. Suppressive effect of Kampo medicine, Cai-pu-tang (Japanese name: Saiboku-to, TJ-96) on brochospasms in aspirin-induced bronchial asthmatic patients and decrease of chronic pain. Especially psychological pain. Itami to Kampo (Pain and Kampo Medicine) 2001; 11: 14-21.
Ishida H, Otake T, Kurihara H, et al. Clinical study on augmentative effect of Saiboku-to for anxiolytic and antidepressive action of diazepam. Pain Clinic, 1999; 20: 395-9.
Yamada T, Bessho K. Clinical evaluation of sai-boku-to (Kampo medicine) for glossodynia. Kampo to Saishin-chiryo (Kampo & the Newest Therapy) 1999; 8: 261-5.
Bessho K, Okubo Y, Hori S, et al. Effectiveness of Kampo medicine (Sai-Boku-To) in treatment of patients with glossdynia. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 1998; 86: 682-6.
Yamada T, Bessho K, Murakami K, et al. Clinical evaluation of sai-boku-to (Kampo medicine) for glossodynia. Shika Yakubutsu Ryoho (Oral Therapeutics and Pharmacology) 1998; 17: 18-22.
Fukushima M. Profiles of effects of traditional oriental herbal medicines on central nervous system in humans – assessment of Saiboku-to and Saiko-ka-ryukotsu-borei-to using EEG and pharmacokinetics of herbal medicine-derived ingredients as indices -. Seishin Shinkeigaku Zasshi (Psychiatria et Neurologia Japonica) 1997; 99: 355-69.
Suzuki S, Furukawa H, Ami H, et al. Experience with TSUMURA Saibokuto (TJ-96) in patients who underwent thyroid or parathyroid surgery. Progress in Medicine 1994; 14: 2254-8.
Egashira Y, Nagano H. A multicenter clinical trial of TJ-96 in patients with steroid-dependent bronchial asthma. A comparison of groups allocated by the envelope method. Annals of the New York Academy of Science 1993; 685: 580-3.
Niitsuma T, Fukuda T, Yamamoto S, et al. Effects of saibokuto and other Saiko-zai (Saiko-drugs) on prednisolone metabolism. Kampo to Meneki-Arerugi (Kampo and Immuno-allergy) 1993; 7: 43-52.
Saito Y, Mitsuhashi N, Takahashi I, et al. Effect of TSUMURA Saiboku-to as an agent for healing damage in treatment of radiomucositis due to irradiation of the head and neck area and mediastinum. Biotherapy 1992; 6: 1899-906.
Yamagiwa M, Sakakura Y, Harada T, et al. Therapeutic response to various drugs in patients with continuous or periodic discomfort in the throat. Jibiinkoka Rinsho (Practica otologica) 1990; 83: 1687-92.
Egashira Y, Nagano H, et al. Results of a comparative clinical study of the effect of “TSUMURA Saiboku-to” (TJ-96) against steroid dependent bronchial asthma in 2 groups, a Saiboku-to administration group and a non-administration group, divided by the envelope method. Kampo to Meneki-Arerugi (Kampo and Immuno-allergy) 1990; 4: 128-44.
Ito S, Mikawa H. Effect of “TSUMURA Saiboku-to” (TJ-96) on bronchial asthma in children. Kampo to Meneki-Arerugi (Kampo and Immuno-allergy) 1990; 4: 115-25.