Chinese: Bai Hu Jia Ren Shen Tang

English: White Tiger plus Ginseng Decoction

Source: Shanghanlun (Treatise on Cold Damage Diseases)

Pulse: large, forceless

Tongue: red dry body, yellow fur

Abdomen: medium abdominal wall strength, shinkahiko

Indications: This herbal formula has been used for patients with following health conditions and symptoms:

  • Fever
  • Profuse sweating
  • Generalized weakness
  • Shortness of breath
  • Dermatitis
  • Dry mouth
  • Diabetes
  • Aversion to heat
  • Metabolic syndrome

There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.

Herbs in This Formula

Note: Suggested dosages of each herb in Kampo formulas are often smaller than those of Traditional Chinese Medicine (TCM). Individual dosages of herbs may be adjusted depending on each patient’s condition, constitutional patterns, quality of the herbs, and other factors involved.

Basic and Clinical Research on Byakkokaninjinto – Updated on June 16, 2012

Hitoshi K, Katoh M, Tanaka Y, Kurono S, Hotta K, Saito H, et al. Mechanism of drug interaction between a Kampo medicine, byakkokaninjinto, and tetracycline in rats. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2012;18(1):75-82.

Aburada T, Ikarashi N, Kagami M, Ichikawa Y, Sugitani M, Maniwa A, et al. Byakkokaninjinto prevents body water loss by increasing the expression of kidney aquaporin-2 and skin aquaporin-3 in KKAy mice. Phytotherapy research : PTR. 2011;25(6):897-903.

Ohnishi M, Hitoshi K, Katoh M, Nadai M, Abe F, Kurono S, et al. Effect of a Kampo preparation, byakkokaninjinto, on pharmacokinetics of ciprofloxacin and tetracycline. Biological & pharmaceutical bulletin. 2009;32(6):1080-4.

Yanagi Y, Yasuda M, Hashida K, Kadokura Y, Yamamoto T, Suzaki H. Mechanism of salivary secretion enhancement by Byakkokaninjinto. Biological & pharmaceutical bulletin. 2008;31(3):431-5.

Sakaguchi M, Goto K, Ichiki H, Hattori N, Iizuka A, Yamamoto M, et al. Effects of Byakko-ka-ninjin-to on salivary secretion and bladder function in rats. Journal of ethnopharmacology. 2005;102(2):164-9.

Morimoto Y, Sakata M, Ohno A, Maegawa T, Tajima S. [Effects of Byakko-ka-ninjin-to, Bofu-tsusho-san and Gorei-san on blood glucose level, water intake and urine volume in KKAy mice]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2002;122(2):163-8.

Tatsumi T, Yamada T, Nagai H, Terasawa K, Tani T, Nunome S, et al. A Kampo formulation: Byakko-ka-ninjin-to (Bai-Hu-Jia-Ren-Sheng-Tang) inhibits IgE-mediated triphasic skin reaction in mice: the role of its constituents in expression of the efficacy. Biological & pharmaceutical bulletin. 2001;24(3):284-90.

Tohda C, Sugahara H, Kuraishi Y, Komatsu K. Inhibitory effect of Byakko-ka-ninjin-to on itch in a mouse model of atopic dermatitis. Phytotherapy research : PTR. 2000;14(3):192-4.

Kimura I, Nakashima N, Sugihara Y, Fu-jun C, Kimura M. The antihyperglycaemic blend effect of traditional chinese medicine byakko-ka-ninjin-to on alloxan and diabetic KK-CA(y) mice. Phytotherapy research : PTR. 1999;13(6):484-8.

Niijima A, Kubo M, Ichiki H, Komatsu Y, Maruno M, Okada M. Effect of byakko-ka-ninjin-to on the efferent activity of the autonomic nerve fibers innervating the sublingual gland of the rat. Journal of the autonomic nervous system. 1997;63(1-2):46-50.

Kimura M, Kimura I, Chem FJ. Combined potentiating effect of byakko-ka-ninjin-to, its constituents, rhizomes of Anemarrhena asphodeloides, tomosaponin A-III, and calcium on pilocarpine-induced saliva secretion in streptozocin-diabetic mice. Biological & pharmaceutical bulletin. 1996;19(7):926-31.