Chinese: Wu Zhu Yu Tang

English: Evodia Decoction

Source: Shanghanlun (Treatise on Cold Damage Diseases)

Pulse: sunken, slow or fine, slow or fine, bowstring

Tongue: pale body, slippery white fur

Abdomen: shinsuion

Indications: This herbal formula has been used for patients with following health conditions and symptoms:

  • Vomiting
  • Headache at the vertex
  • Migraine
  • Cold hands and feet
  • Dizziness
  • Fluid retention
  • Gastritis
  • Indigestion

There are many other health conditions that may respond well to this herbal formula, in particular patients exhibiting indicative traditional diagnostic signs and symptoms.

Herbs in This Formula

Note: Suggested dosages of each herb in Kampo formulas are often smaller than those of Traditional Chinese Medicine (TCM). Individual dosages of herbs may be adjusted depending on each patient’s condition, constitutional patterns, quality of the herbs, and other factors involved.

Abdominal pattern (fukusho) of Goshuyuto (from Fukusho Kiran, 1800)


Basic and Clinical Research on Goshuyuto (Wu Zhu Yu Tang) – Updated on Mar. 30, 2011

Odaguchi H, Wakasugi A, Ito H, et al. The efficacy of goshuyuto, a typical Kampo (Japanese herbal medicine) formula, in preventing episodes of headache. Current Medical Research and Opinion 22: 1587-97 (2006)

Maruyama T. Goshuyu-to versus lomerizine hydrochloride in the prophylactic treatment of migraine headaches: an open crossover trial. Itami to Kampo (Pain and Kampo Medicine) 16: 30-9 (2006)

Odaguchi H, Hanawa Y. Complementary alternative medicine in headache treatment. Igaku no Ayumi (Journal of Clinical and Experimental Medicine) 215: 1137-40 (2005)

Higuchi K, Arakawa T, Ando K, et al. Eradication of Helicobacter pylori with a Chinese Herbal medicine without emergence of resistant colonies. American Journal of Gastroenterology 94: 1419-20 (1999)

Seki H, Okita N, Takase S, et al. Pain-relieving effect of goshuyuto on chronic headache: comparison with keishininjinto (with randomization carried out using the sealed-envelope method). Pharma Medica 11: 288-91 (1993)

Otake T, Kato I, Saito S, et al. The prophylactic effect of “Gosyuyu-to” and “Gorei-san” for post-spinal headache. Pain Clinic 12: 648-52 (1991)

Seki H, Tateyama M, Sahara M, et al. Pain-relieving effect of goshuyuto on chronic headache: comparison with keishininjinto (with randomization using the sealed-envelope method)*. Shinryo to Shinyaku (Medical Consultation & New Remedies) 28: 573-6 (1991)